• We are a group of scientists and clinicians researching how damage to our DNA drives the aging process and diseases like cancer.
  • We are a group of scientists and clinicians researching how damage to our DNA drives the aging process and diseases like cancer.
  • We are a group of scientists and clinicians researching how damage to our DNA drives the aging process and diseases like cancer.

Our Core Research Team

We are twelve independent laboratories working together to find new ways to prevent cancers, better treat cancers and understand how they arise.

Dr. Aaron Goodarzi

Dr. Aaron Goodarzi

Understanding oxidative DNA damage after radiation exposure

Short Bio Summary

Dr. Goodarzi is the Canada Research Chair for Radiation Exposure Disease. He obtained his PhD from University of Calgary in 2005 and trained as a post-doctoral scholar at the Genome Damage and Stability Centre at the University of Sussex (UK) until 2010. In 2011, he opened his own laboratory at the University of Calgary’s School of Medicine. In 2015, he was named one of Calgary's Top 40 Under 40 and, in 2016 he was made a University of Calgary “Peak Scholar” for his work in knowledge engagement and innovation with regards to radon gas induced cancer. Dr. Goodarzi is the founder and leader of Evict Radon, a national confederation of scholars aimed at enabling radon research by encouraging citizens to test for radon and share their findings with researchers

Research Interests

From the moment of our conception, our DNA is subject to damage, the most serious form being a break in both strands of the DNA double helix. Unless these breaks are resealed correctly, whole segments of our genome can be lost or irrevocably mutated to fuel a self-propagating process of volatility that underlies cancer formation, radiation poisoning and/or premature cellular aging. Our research focuses on slow-repairing DNA double strand breaks induced within densely compacted heterochromatin and/or by high linear energy transfer ionizing radiation such as alpha particles emitted by radon gas. We are especially curious about DNA double-strand break repair processes involving nucleosome remodeling enzymes. We are taking forward our discoveries into the community, conducting wide-scale radon gas exposure testing and aiming to understand how the radiation emitted by radon impacts our bodies and who, based on our genetics, may be the most sensitive to cancer following radon exposure. Discoveries in these areas are improving our knowledge of cancer formation, human ageing and radiation protection.

Laboratory Members

Lab Manager:
Shilpa Salgia
Lab Technician:
Carin Pihl
Lab Technician:
Shujuan Fang
Post Doctoral Fellow:
Wilson Nartey
Post Doctoral Fellow:
Shaun Moore
Post Doctoral Fellow:
Peter Brownlee
PhD Student:
Fintan Stanley
PhD Student:
Dustin Pearson
PhD/MD Student:
Daniel Berger
MSc Student:
Luc Provencher
PhD Student:
John Danforth
Summer Student 2018:
Jesse Irvine

Productivity & Funding

Publications

pubmed

Media & TEDx Talk

facebook

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Current Funding

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Our annual lab photo shoot!Lab2017 Horizontal Low Res

Lab 2015-16 Low Res

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